Key Takeaways (TL;DR):
- Atletico Madrid remain unbeaten at home this season.
- Juan Musso starts as goalkeeper for Atletico.
- Diego Simeone’s Atletico have defensive challenges but key players like José Gimenez and Matteo Ruggeri play.
- Giuliano Simeone and Pablo Barrios bolster Atletico’s midfield.
- Inter Milan face the match with some changes; Stefan de Vrij is reinstated in defense.
- Luis Henrique returns to Inter’s starting lineup.
- Inter miss Denzel Dumfries and Matteo Darmian due to injury.
- Lautaro Martinez leads Inter’s attack.
Overview
Atletico Madrid host Inter Milan at the Riyadh Air Metropolitano Stadium in Madrid on Wednesday, Nov. 26, with kickoff at 3 p.m. ET. Atletico come off five straight wins in La Liga and an unbeaten home Champions League run this season, while Inter Milan lead the Champions League group stage with four wins. Both teams have a strong chance to earn important points in this crucial matchday five of the UEFA Champions League.
- Fixture: Atletico Madrid vs Inter Milan
- Competition: UEFA Champions League
- Venue: Riyadh Air Metropolitano, Madrid, Spain
- Date: Wednesday, 26 November 2025
- Kick-off: 20:00 GMT / 15:00 ET / 12:00 PT
- Referee: Francois Letexier (France)
Predicted Lineup
Atletico Madrid (4-4-2):
Juan Musso, Nahuel Molina, José Gimenez, David Hancko, Matteo Ruggeri, Giuliano Simeone, Pablo Barrios, Koke, Nicolás González, Alexander Sørloth, Julián Álvarez
Inter Milan (3-5-2):
Yann Sommer, Manuel Akanji, Stefan de Vrij, Alessandro Bastoni, Carlos Augusto, Nicolo Barella, Hakan Çalhanoğlu, Piotr Zieliński, Federico Dimarco, Luis Henrique, Lautaro Martínez
Injury Report
Atletico Madrid
- Marcos Liorenter
- Jan Oblak
- Robin Le Normand
Inter Milan
- Henrikh Mkhitaryan
-
Raffaele Di Gennaro
- Tomas Palacios
- Denzel Dumfries (injured)
- Matteo Darmian (injured)
Analysis Report
Atletico Madrid’s solid home form and attacking duo of Sørloth and Álvarez give them confidence, supported by a stable backline and hardworking midfield including Giuliano Simeone. Their defensive fitness is crucial against a strong Inter Milan side.
Inter Milan, with reinforcements like Stefan de Vrij and Luis Henrique returning, will look to leverage their strong midfield and dynamic attack led by Lautaro Martínez. Despite injuries to Dumfries and Darmian, they remain top contenders in the group.
Both teams are highly motivated and evenly matched, making a draw a likely outcome, though Atletico’s home advantage may push for a slight edge.